Dopamine receptors

Every compound in the sci-wiki that affects dopamine receptors; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

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Analgesic

Tetrahydropalmatine

L-THP (levo-tetrahydropalmatine) is a plant alkaloid from Corydalis and related herbs with a long history in traditional Chinese medicine for its calming, sedative, and pain-relieving properties. Modern research has clarified its mechanism as a dopamine receptor modulator, and it has been carried all the way into a human clinical study for cocaine use disorder, an unusually strong evidence base for a botanical compound. For those exploring natural approaches to relaxation, sleep, and discomfort, L-THP is a genuinely well-studied and intriguing choice.

1 outlet

Gastrointestinal

Metoclopramide

Metoclopramide is a medication that relieves nausea and vomiting and stimulates the movement of the upper digestive tract. Belonging to the benzamide class and acting mainly as a dopamine D2 receptor blocker, it is used for conditions such as chemotherapy-induced and post-surgical nausea, gastroparesis, and gastroesophageal reflux, and it is sold under brand names including Reglan and Maxolon. Because it can cause movement-related side effects with prolonged use, treatment courses are usually kept short, and it appears on the World Health Organization's list of essential medicines.

1 outlet