Cell Proliferation

Every compound in the sci-wiki that affects cell proliferation; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

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Antineoplastic

Methotrexate

Methotrexate is an antimetabolite drug of the antifolate class used both as a cancer chemotherapy agent and, in much lower doses, as an immune-modulating treatment for autoimmune disease. By interfering with the body's use of folate, it blocks the synthesis of DNA and slows the growth of rapidly dividing cells, which underlies its use against several cancers. At low weekly doses it is a first-line disease-modifying drug for rheumatoid arthritis and is also used in psoriasis, other autoimmune conditions, and to end ectopic and molar pregnancies.

1 outlet

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Antineoplastic

Erdafitinib

Erdafitinib (brand name Balversa) is an oral targeted cancer drug that blocks the fibroblast growth factor receptor (FGFR) family, a set of receptors that push cells to grow and divide. It is approved for advanced bladder (urothelial) cancer in people whose tumors carry FGFR2 or FGFR3 genetic changes. By shutting down that growth signal, it slows or shrinks tumors that lean on FGFR to keep expanding.

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