Cartilage

Every compound in the sci-wiki that affects cartilage; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

2 sourced · 1 reference

←cartilage3/3

Peptide

AOD-9604

AOD-9604 is a synthetic peptide fragment of human growth hormone, corresponding to the C-terminal lipolytic domain (residues 176-191) with an added tyrosine, engineered to trigger fat breakdown without the blood-sugar and growth side effects of full growth hormone. In obese animals it reduced body weight and body fat and increased fat oxidation, while notably not impairing insulin sensitivity the way intact growth hormone does [1][3]. It is marketed as a fat-loss and recovery peptide, though it never gained approval as an anti-obesity drug and its human weight-loss data are limited [4].

6 outlets

Supplement

Pentosan Polysulfate Sodium

Pentosan polysulfate sodium is a semisynthetic, sulfated polysaccharide with heparin-like properties, used mainly as an oral medicine for interstitial cystitis, a chronic bladder pain condition. Manufactured from beechwood xylan and sold under the brand name Elmiron, it is the only oral drug approved in the United States for that indication. In recent years it has drawn attention because prolonged use has been linked to a distinctive form of retinal damage.

1 outlet

reference shelf; no outlet carries these yet

Peptide

Vosoritide

Vosoritide (brand name Voxzogo) is a lab-made version of C-type natriuretic peptide (CNP, a natural molecule that helps regulate bone growth). It is approved to help children with achondroplasia (the most common form of dwarfism) grow taller by targeting the overactive growth signal behind the condition. It works as a counter-signal to FGFR3, the receptor that, when overactive, holds back the growth plates in the long bones.

reference