Bacterial folate synthesis

Every compound in the sci-wiki that affects bacterial folate synthesis; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

1 sourced · 1 reference

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Blend

Sulfamethoxazole + Trimethoprim

Sulfamethoxazole and trimethoprim, given together as a fixed-dose combination known as co-trimoxazole, is a widely used antibiotic. The two drugs block successive steps in the pathway bacteria use to make folate, producing a synergistic effect stronger than either alone. It treats infections including urinary tract infections, certain respiratory and skin infections, and is a first-line agent for Pneumocystis pneumonia in people with weakened immune systems.

2 outlets

reference shelf; no outlet carries these yet

Antibacterial

Acediasulfone

Acediasulfone is a sulfone-class antibacterial that functions as a water-soluble, longer-acting prodrug of dapsone, historically used in the treatment of leprosy (Hansen's disease).

reference