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compare compounds

class, effects, and the receptor fingerprint, side by side; add up to four, then source the whole stack

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reading the marksactivatesblocks / inhibitsmodulates

81Opi

Hydromorphone

OpioidSerious Drug

effects: Opioid receptors
suppliers: reference only

Receptor fingerprint

Mu-opioid receptorFull agonist

strong

81Opi

Morphine

OpioidAnalgesic

effects: Mu-opioid receptor, Pain, Dopamine
suppliers: reference only

Receptor fingerprint

Mu-opioid receptor (OPRM1)agonist

strong

Kappa-opioid receptor (OPRK1)agonist

weak

Delta-opioid receptor (OPRD1)agonist

weak

Mu-delta opioid receptor heteromermodulates

moderate

Toll-like receptor 4 (TLR4 / MD2)modulates

weak

Add compound

no matches for “”

stack compatibility

OverallAvoid

checking Hydromorphone and Morphine: at least one combination is flagged to avoid (1 to avoid). treat the red pairs as a reason to reconsider mixing.

Hydromorphone + Morphine
Avoid
two strong CNS depressants (opioid, benzodiazepine, z-drug, barbiturate, gabapentinoid, GABAergic or alcohol) add together on sedation and breathing; a leading cause of fatal respiratory depression.

Check interactions →

General educational info, not medical advice.